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Priobiotics Against Parasites; Research Crowdfunding Project Launched

Nielsen has launched the first research crowdfunding project at UK and possibly the first such effort in the field of veterinary science.

Horses on UK's Maine Chance Farm are a part of equine parasitology research conducted by Dr. Martin Nielsen.
Photo Copyright Stephen Patton

January 8, 2014--Martin Nielsen,DVM, PhD, DEVPC, DACVM, equine parasitologist, veterinarian and assistant professor at the University of Kentucky's Gluck Equine Research Center, has launched the first research crowdfunding project at UK and possibly the first such effort in the field of veterinary science.

Crowdfunding is a relatively new term that describes reaching out to the general public, usually through the Internet, to reach a fundraising goal. Success in reaching the goal often depends on many individuals making small donations through a website.

Nielsen’s crowdfunding campaign, called “Let the germs get the worms: Testing a novel probiotic compound for treatment of equine parasites,” is hosted at the website http://equineparasitology.ca.uky.edu/ and has a goal of raising $30,000 before March 10.

Nielsen’s research team is devoted to providing solutions for worm control in horses. Horse parasites, such as small strongyles and large roundworm, are developing increased levels of resistance to all available dewormers. No new drugs are being developed for use in horses, so the equine industry needs new reliable treatment alternatives. Horses on pasture are constantly exposed to different parasite types. These can cause disease symptoms such as colic, diarrhea and weight loss. Foals are particularly vulnerable to parasite infection and need special attention in parasite control programs.

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“It is our experience that horse owners are very interested in updated information about parasite control and have great concerns about drug resistance,” Nielsen said. “We therefore felt that crowdfunding would be very appropriate for raising funding for research in this area. The crowdfunding platform allows direct interaction with the end users of our research, which is very valuable to us. A good question can inspire us to set up the next research project.”

Researchers at the University of California have identified a naturally occurring bacterium, Bacillus thuringiensis, which produces a crystal protein capable of killing intestinal worms without harming the animal. UK’s study aims to evaluate the effect of this bacterial protein against important horse parasites under laboratory conditions. Parasites will be collected from horses in a research herd and tested in the laboratory.

“We will test for the presence of receptors for the bacterial protein, and test the effect against different horse parasites under laboratory conditions,” Nielsen said. “We expect to use the results to apply for a larger grant to finally allow us to test the probiotic in horses.”

“We are proud of this innovative approach to fundraising which gives the donors a chance to participate in the research program and research findings,” said Nancy Cox, PhD, dean of the UK’s College of Agriculture, Food and Environment and Kentucky Agricultural Experiment Station director. “We are pleased that Dr. Nielsen’s crowdfunding project is the very first one to be implemented at UK.”

Guests can sign up for more information on the project and make online donations at http://equineparasitology.ca.uky.edu/,where they can also access videos and educational information. As a special feature, the site is set up with an exclusive questions forum where visitors can ask Nielsen about parasite control.

The mission of the Gluck Center, a UK Ag Equine program, is scientific discovery, education and dissemination of knowledge for the benefit of the health and well-being of horses. The Gluck Center faculty conducts equine research in six targeted areas: genetics and genomics, infectious diseases and immunology, musculoskeletal science, parasitology, pharmacology/toxicology and reproductive health. For more information on the Gluck Center visit http://www.ca.uky.edu/gluck.

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